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Rev. Inst. Med. Trop. Säo Paulo ; 49(2): 113-116, Mar.-Apr. 2007. ilus
Article in English | LILACS | ID: lil-449798

ABSTRACT

This report describes two patients who presented acute disseminated and severe toxoplasmosis as the first opportunistic disease related to acquired immunodeficiency syndrome. At admission, clinical and laboratory findings were similar to sepsis or septic shock and a fast evolutive course to death occurred in both cases. At necropsy, an inflammatory reaction and presence of a great number of Toxoplasma gondii cysts and tachyzoites were observed in most organs examined.


O presente relato descreve dois pacientes que apresentaram toxoplasmose aguda, disseminada e grave como primeira manifestação oportunista da síndrome da imunodeficiência adquirida. Os achados clínicos e laboratoriais foram similares aos de sepse ou choque séptico e, em ambos os casos houve evolução rápida para óbito. A necropsia, foi observada reação inflamatória e presença de taquizoítos e cistos de Toxoplasma gondii na maioria dos órgãos examinados.


Subject(s)
Humans , Animals , Female , Adult , AIDS-Related Opportunistic Infections/diagnosis , Sepsis/diagnosis , Toxoplasmosis/diagnosis , Acute Disease , AIDS-Related Opportunistic Infections/parasitology , AIDS-Related Opportunistic Infections/pathology , Fatal Outcome , Severity of Illness Index , Sepsis/pathology , Toxoplasma/isolation & purification , Toxoplasmosis/pathology
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